TRK fusions can drive development of a wide range of tumor types, including those you commonly see—and those you don’t. 1-3

TRK fusion cancer is heterogeneous, occurring across diverse tissue and cell lineages. 1-3

To date, oncogenic TRK fusions have been identified in at least 25 cancers, including 1-3

Head and Neck Cancers

Thoracic Cancers

Breast Cancers

Gastrointestinal Cancers


CNS Cancers

Genitourinary Cancers

Hematological Malignancies

Other Cancers

TRK fusion cancer currently has no known defining clinical or pathological features.
Only testing can determine its presence. 1

TRK fusion cancer sites

CNS=central nervous system.